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Fig. 2 | International Journal of Health Geographics

Fig. 2

From: Light at night exposure and risk of dementia conversion from mild cognitive impairment in a Northern Italy population

Fig. 2

Spline correlation analysis between outdoor artificial light at night (LAN) exposure and levels of cerebrospinal biomarkers, i.e. beta-amyloid, total tau protein, phosphorylated tau-protein. Light and dark red dots indicate subjects who remained MCI and converted to dementia, respectively. The blue line represents spline regression analysis with 95% confidence interval (light blue area). The red continuous line represents the biomarker cut-off values used at the Modena Neuroimmunology Laboratory (amyloid Aβ1−42: 557 pg/mL; t-tau: 350 pg/mL; p-tau181: 62 pg/mL)

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